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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CALR
All Species:
56.97
Human Site:
S69
Identified Species:
83.56
UniProt:
P27797
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27797
NP_004334.1
417
48142
S69
K
D
K
G
L
Q
T
S
Q
D
A
R
F
Y
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110217
417
48095
S69
K
D
K
G
L
Q
T
S
Q
D
A
R
F
Y
A
Dog
Lupus familis
XP_853393
417
48162
S69
K
D
K
G
L
Q
T
S
Q
D
A
R
F
Y
A
Cat
Felis silvestris
Mouse
Mus musculus
P14211
416
47976
S69
K
D
K
G
L
Q
T
S
Q
D
A
R
F
Y
A
Rat
Rattus norvegicus
P18418
416
47977
S69
K
D
K
G
L
Q
T
S
Q
D
A
R
F
Y
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514084
419
48477
S70
K
D
K
G
L
Q
T
S
Q
D
A
R
F
Y
A
Chicken
Gallus gallus
XP_418262
419
48016
S82
R
D
R
G
L
Q
T
S
E
N
S
K
F
Y
A
Frog
Xenopus laevis
NP_001080765
413
48503
S70
K
D
K
G
L
Q
T
S
Q
D
A
R
F
Y
A
Zebra Danio
Brachydanio rerio
NP_956007
419
48936
S70
K
D
K
G
L
Q
T
S
Q
D
A
H
F
Y
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29413
406
46790
S69
A
D
K
G
I
Q
T
S
Q
D
A
R
F
Y
A
Honey Bee
Apis mellifera
XP_392689
403
47156
S68
N
D
K
G
I
Q
T
S
Q
D
A
R
F
Y
A
Nematode Worm
Caenorhab. elegans
P27798
395
45598
D66
Q
G
I
Q
T
S
Q
D
A
K
F
Y
S
R
A
Sea Urchin
Strong. purpuratus
NP_999643
421
48804
S68
Q
D
K
G
I
Q
T
S
Q
D
A
K
F
Y
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9SP22
420
47921
S75
E
D
K
G
I
Q
T
S
E
D
Y
R
F
Y
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38858
424
48138
S72
N
D
K
G
I
Q
T
S
E
D
Y
R
F
Y
A
Baker's Yeast
Sacchar. cerevisiae
P27825
502
56949
G89
K
G
I
A
V
R
T
G
N
A
A
A
M
I
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
94.9
N.A.
94.2
93.7
N.A.
84
59.6
78.1
74.4
N.A.
64.2
66.9
62.5
64.8
Protein Similarity:
100
N.A.
99.7
97.3
N.A.
97.5
97.3
N.A.
92.3
73.9
90.1
85.9
N.A.
76.5
77.6
75.3
79.3
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
60
100
93.3
N.A.
86.6
86.6
6.6
73.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
93.3
93.3
13.3
93.3
Percent
Protein Identity:
N.A.
52.1
N.A.
51.4
26.1
N.A.
Protein Similarity:
N.A.
70
N.A.
68.1
40.8
N.A.
P-Site Identity:
N.A.
73.3
N.A.
73.3
20
N.A.
P-Site Similarity:
N.A.
93.3
N.A.
86.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
0
0
0
7
7
75
7
0
0
88
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
88
0
0
0
0
0
7
0
82
0
0
0
0
0
% D
% Glu:
7
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
7
0
88
0
0
% F
% Gly:
0
13
0
88
0
0
0
7
0
0
0
0
0
0
13
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
13
0
32
0
0
0
0
0
0
0
0
7
0
% I
% Lys:
57
0
82
0
0
0
0
0
0
7
0
13
0
0
0
% K
% Leu:
0
0
0
0
57
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
13
0
0
0
0
0
0
0
7
7
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
13
0
0
7
0
88
7
0
69
0
0
0
0
0
0
% Q
% Arg:
7
0
7
0
0
7
0
0
0
0
0
69
0
7
0
% R
% Ser:
0
0
0
0
0
7
0
88
0
0
7
0
7
0
0
% S
% Thr:
0
0
0
0
7
0
94
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
13
7
0
88
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _